Drug Discovery
R&D Collaborations
  • This Product line automatically quantifies the behavior of small animals cultured in microtiter plates.
  • Compatible with: C. elegans, drosophila, zebrafish, xenopus larvae and similar sized organisms.
  • Suitable for microplates (6 to 384 wells); liquid media.
  • Non invasive infrared detection method. 384 simultaneous channels.*
  • *Patents: US12515723 and EP2086408B1
    Distributed in association with Designplus SRL

WMicroTracker gives you the capability to measure in an easy, fast and highly reproducible way the locomotive activity of small animals cultured in microtiter plates. The system can be used in High-Throughput Screening assays to identify and evaluate the biological effects of new potential compounds/drugs, RNAi or morpholinos, as well as mutants studies in the model organisms like C. elegans worms, D. rerio zebrafish larvae, X. laevis frog tadpole, Anopheles sp. mosquitoes, and similar sized animals.

====== Own References ======
Reliable Screening of Dye Phototoxicity by Using a Caenorhabditis elegans Fast Bioassay.
Bianchi JI et al. PLoS One. 2015
Set-up of an infrared fast behavioral assay using zebrafish (Danio rerio) larvae, and its application in compound biotoxicity screening.
Bichara D et al. Journal of Applied Toxicology. 2014
Towards an Automatic Method for Toxicity and Pharmacological Testing in C. elegans
Simonetta SH. Worm Breeder's Gazette. 2010
An automated tracking system for Caenorhabditis elegans locomotor behavior and circadian studies application.
Simonetta SH et al. Journal of Neurosciences Methods. 2007
====== Third party References(applied sc) ======
Development of Nutraceutical Emulsions as Risperidone Delivery Systems: Characterization and Toxicological Studies.
Igartua DE et al. Universidad Nacional de Quilmes, ARGENTINA. J Pharm Sci. 2015
Bioactivity Of Nanosilver In Caenorhabditis Elegans: Effects Of Size, Coat, And Shape.
Hunt PR et al. FDA, Laurel, MD, USA. Toxicology Reports. 2014
====== Third party References(fundamental sc) ======
FET proteins regulate lifespan and neuronal integrity.
Therrien M et al. Universite de Montreal, CANADA. Scientific Reports. 2016
Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.
Veriepe J et al. Universite de Montreal, CANADA. Nature Communications. 2015
Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle.
Matsunaga Y et al. Emory University, Atlanta, GA, USA. Mol Biol Cell. 2015
Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling.
Detienne G et al. KU Leuven, BELGIUM. Experimental Gerontology. 2014
The nervous and prenervous roles of serotonin in Echinococcus spp.
Camicia F et al. Int J Parasitol. University of Buenos Aires, ARGENTINA. 2013
PDF receptor signaling in Caenorhabditis elegans modulates locomotion and egg-laying.
Meelkop E et al. KU Leuven, BELGIUM. Molecular and Cellular Endocrinology. 2012
Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegans.
Tan KT et al. Academia Sinica, Taipei, TAIWAN. Cell Metabolism. 2011